Vusi Kunene (Mr Kipruto) was cast in HOMELANDS directed by Neal Sundstrom in 1996 and in 1997 he appeared in DEAFEANING SILENCE directed by Ettienne De Villiers, both for SABC Television.
In 1998 he was cast in the drama series JUSTICE FOR ALL directed by Peter Goldsmid, for which he won an Avanti award for Best Actor. He was nominated for an NTVA award for Best Actor for his role of Daniel Mofokeng in HOMELANDS and was nominated for the same award three years in a row (2002-2004) for his role as Jack Mabaso in GENERATIONS.
In 1996 he was cast in two feature films: FOOLS directed by Ramadan Suleman, and Kini and Adams (in which he played the lead role of Kini), directed by Idrissa Ouedraogo for Framework, Zimbabwe.
In 1998 he was cast in A REASONABLE MAN directed by Gavin Hood and then THE KING IS ALIVE, a Dogma production which was directed by Kristian Levring and filmed in Namibia in 1999.
Later film roles included FINAL SOLUTION (2001) and the made-for-TV movie/mini-series DIAMOND HUNTERS also in 2001.
In 2008 he played the role of Doctor Gulubane in the pilot episode of THE NO.1 LADIES DETECTIVE AGENCY directed by the late Anthony Minghella.
He has a starring role in the 10th season of the SABC1 drama series SOUL CITY, in 2010.